quinapril

What is the most important information I should know about quinapril?

If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).

What is quinapril?

Quinapril is used in adults alone or in combination with other medications to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Quinapril is also used in adults together with other medications to treat heart failure.

Quinapril may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking quinapril?

• have a history of angioedema; or
• you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, ramipril, or trandolapril.

Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking quinapril with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;
• heart problems;
• low blood pressure;
• high blood levels of potassium (hyperkalemia);
• if you are on a low-salt diet;
• low white blood cell counts;
• diabetes;
• kidney disease (or if you are on dialysis); or
• liver disease.

How should I take quinapril?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested.

Tell your doctor if you have a planned surgery.

If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

What should I avoid while taking quinapril?

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Avoid strenuous exercise if you are being treated for heart failure. Ask your doctor about your risk.

What are the possible side effects of quinapril?

• chest pain, fast, slow, or uneven heart rate;
• a light-headed feeling, like you might pass out;
• heart problems --swelling, rapid weight gain, feeling short of breath;
• kidney problems --swelling, urinating less, feeling tired or short of breath;
• liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), abnormal liver function tests;
• signs of infection --fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or
• high blood potassium --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects may include:

• headache;
• nausea, vomiting, stomach pain;
• cough; or
• dizziness, tiredness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect quinapril?

Tell your doctor about all your other medicines, especially:

• lithium;
• a diuretic or "water pill";
• gold injections to treat arthritis;
• temsirolimus, sirolimus, or everolimus; or
• NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about quinapril.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 18.01. Revision date: 6/21/2023.