epoetin beta and methoxy polyethylene glycol
What is the most important information I should know about epoetin beta and methoxy polyethylene glycol?
You should not use this medicine if you have uncontrolled high blood pressure or if you have ever had pure red cell aplasia.
This medicine is not for treating anemia caused by cancer chemotherapy.
This medicine can increase your risk of serious or fatal side effects, including heart attack, stroke, or blood clot. Call your doctor or get emergency medical help if you have symptoms such as: chest pain, trouble breathing, sudden numbness or weakness, a cold or pale arm or leg, confusion, or problems with speech or balance.
What is epoetin beta and methoxy polyethylene glycol?
Epoetin beta and methoxy polyethylene glycol is a combination medicine used to treat anemia (lack of red blood cells) and to reduce the need for blood cell transfusions.
Epoetin beta and methoxy polyethylene glycol is used to treat anemia caused by chronic kidney disease in adults, or in children at least 5 years old who are on hemodialysis.
This medicine is not for treating anemia caused by cancer chemotherapy. Epoetin beta and methoxy polyethylene glycol may increase tumor growth or decrease survival time in people with certain types of cancer.
Epoetin beta and methoxy polyethylene glycol should not be used to take the place of an emergency blood cell transfusion.
Epoetin beta and methoxy polyethylene glycol may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before using epoetin beta and methoxy polyethylene glycol?
You should not use this medicine if you are allergic to epoetin beta or methoxy polyethylene glycol, or if you have:
- uncontrolled hypertension (high blood pressure); or
- if you have ever had a type of anemia called pure red cell aplasia (PRCA).
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using epoetin beta and methoxy polyethylene glycol.
Tell your doctor if you have ever had:
- heart disease, high blood pressure;
- a seizure;
- dialysis treatment; or
- cancer.
Tell your doctor if you are pregnant or breastfeeding.
How should I use epoetin beta and methoxy polyethylene glycol?
This medicine is usually given once every 2 weeks or once per month. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Epoetin beta and methoxy polyethylene glycol is injected under the skin or given as an infusion into a vein. When used in a child, the medicine should be given only into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.
Your blood pressure will need to be checked often. You will also need frequent medical tests, and your next dose may be delayed based on the results.
Call your doctor if you have signs that your body is not responding to this medicine (pale skin, unusual tiredness, lack of energy, dizziness, fainting).
Your doctor may have you take an iron supplement. Take only the type and amount your doctor prescribes.
If you need surgery, tell your surgeon you currently use epoetin beta and methoxy polyethylene glycol. You may need to take medicine to prevent blood clots for a short time after your surgery.
Store prefilled syringes in the refrigerator. Do not freeze or shake. Keep the medicine in the original container until you are ready to give an injection.
You may also store a prefilled syringe at cool room temperature, but you must use the syringe within 30 days or throw it away. Protect from light.
Each prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using epoetin beta and methoxy polyethylene glycol?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of epoetin beta and methoxy polyethylene glycol?
Get emergency medical help if you have signs of an allergic reaction (hives, itching, sweating, wheezing, difficult breathing, dizziness, swelling in your face or throat, fainting) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
This medicine can increase your risk of serious or fatal side effects. Call your doctor or get emergency medical help if you have:
- increased blood pressure --severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed;
- symptoms of heart failure --shortness of breath (even with mild exertion), swelling, rapid weight gain;
- heart attack symptoms --chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; or
- signs of a stroke or blood clot --sudden numbness or weakness (especially on one side of the body), slurred speech, sudden confusion, problems with vision or balance, a cold or pale arm or leg.
Also call your doctor at once if you have a seizure (convulsions), or signs that you may have a seizure, such as:
- sudden mood changes;
- unusual tiredness;
- sensitivity to light or noise; or
- trouble concentrating.
Common side effects may include:
- diarrhea; or
- stuffy nose, sinus pain; or
- sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect epoetin beta and methoxy polyethylene glycol?
Other drugs may affect epoetin beta and methoxy polyethylene glycol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information?
Your pharmacist can provide more information about epoetin beta and methoxy polyethylene glycol.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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