Dihydroergotamine Metered Dose Nasal Spray (DIHYDROERGOTAMINE - NASAL)

For migraine headaches.

Brand Name(s): Migranal

Generic Name: Dihydroergotamine

Instructions

Keep the medicine at room temperature. Avoid heat and direct light.

This medicine is for use in the nose. Avoid getting the medicine into the eyes or mouth. Rinse the eyes with water if the medicine is sprayed into the eyes.

This medicine should be used after a migraine headache starts. It should not be used to prevent a migraine headache.

Ask your doctor, nurse or pharmacist to show you how to use this medicine correctly.

The first time you open a new spray, you need to get it ready to use. Point the bottle away from you and spray into the air four times. It is now ready to use. This process is called priming the spray.

Read and carefully follow package instructions for preparing the pump. Do not assemble the pump until you are ready to use it.

Blow and wipe your nose with a clean tissue before using this product.

Do not sniff through the nose or tilt the head back while using the spray or immediately afterwards.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

You may stop using this medicine if you no longer have symptoms.

Discard any unused medicine after 8 hours.

Do not share this medicine with anyone who has not been prescribed this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than twice during 24 hours.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.

Do not use the medication any more than instructed.

Using this medicine for 10 or more days in a month may make the headaches worse.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

Avoid smoking while on this medicine. Smoking may increase your risk for stroke, heart attack, blood clots, high blood pressure, and other diseases of the heart and blood vessels.

Do not breastfeed while on this medicine. You may safely start breastfeeding 3 days after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • dizziness
  • irritation inside the nose
  • nausea
  • changes in taste or unpleasant taste

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • chest or jaw pain
  • feeling cold or numb, especially in arms and legs
  • cold hands or feet
  • numbness or tingling in hands and feet
  • fast, irregular, or slow heartbeat
  • mood changes
  • muscle pain
  • pale or blue skin, lips or fingernails
  • stomach pain
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • unusual or unexplained tiredness or weakness
  • blurring or changes of vision

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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