Daratumumab/Hyaluronidase Injection (DARATUMUMAB/HYALURONIDASE - SUBCUTANEOUS INJECTION)

This medicine is used for the following purposes:

  • amyloidosis
  • cancer

Brand Name(s): Darzalex Faspro

Generic Name: Daratumumab-fihj/Hyaluronidase-fihj

Instructions

This medicine is used by injecting it into the skin. Please ask your doctor, nurse or pharmacist for the correct places on your body where this medicine can be injected.

This medicine should be given by a trained health care provider.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.

This medicine can cause birth defects. Speak with your doctor about birth control methods that should be used while on this medicine.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women must use reliable forms of birth control while taking this medicine and for 3 months after stopping to prevent pregnancy.

This medicine should be used with caution in patients with breathing difficulties.

Call your doctor right away if you notice any unusual bleeding or bruising.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • agitated feeling or trouble sleeping
  • decreased appetite
  • back pain
  • pain, redness, swelling near injection
  • pain in the joints
  • unusual or unexplained tiredness or weakness

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bleeding or bruising
  • blurry vision
  • chest pain
  • cough that does not go away
  • dizziness
  • swelling of the legs, feet, and hands
  • pain in the eye
  • fainting
  • fever or chills
  • numbness or tingling in hands and feet
  • headaches
  • fast or irregular heart beats
  • hoarseness or throat irritation
  • itching
  • itchy nose
  • nausea and vomiting
  • red, burning, or itchy skin
  • runny or stuffy nose
  • shortness of breath
  • sore throat
  • throat tightness

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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