Vonicog Alfa Injection (VON WILLEBRAND FACTOR, RECOMBINANT - INJECTION)

For bleeding disorder.

Brand Name(s): Vonvendi

Generic Name: Vonicog Alfa (Von Willebrand Factor, Recombinant)

Instructions

This medicine is given as an IV injection into a vein.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

The medicine needs to be mixed before being injected.

Dilute the powder with the liquid provided. Gently swirl the vial until the medicine is completely dissolved. Do not shake the vial.

Do not dilute the medicine until ready to use.

Always inspect the medicine before using.

The liquid should be clear and colorless.

Do not use the medicine if it contains any particles or if it has changed color.

Store at room temperature or in refrigerator. Do not freeze. Protect from light.

Do not store above 86 degrees F (30 degrees C).

Do not store in the bathroom.

If your medicine is stored in the refrigerator, take it out of the refrigerator before use to warm to room temperature.

Inject the medicine immediately after mixing.

Injecting cold drug may be uncomfortable.

Speak with your nurse or pharmacist about how long the medicine can be stored safely at room temperature or in the refrigerator before it needs to be discarded.

Never use any medicine that has expired.

Discard mixed medicine after 3 hours at room temperature.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

Wash your hands before and after handling this medicine.

You or a family member can be trained to give this medicine at home.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

It is very important that you follow your doctor's instructions for all blood tests.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Always carry an ID card or wear a medical alert bracelet indicating your medical condition.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • feeling of heat or flushing
  • headaches
  • pain, redness, swelling near injection
  • nausea
  • rapid heartbeat

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • chest pain
  • confusion
  • severe or persistent headache
  • fast or irregular heart beats
  • sudden leg pain, swelling, warmth or redness
  • shortness of breath
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • sudden change or loss of vision

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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